ALT cancer cells are specifically sensitive to lysine acetyl transferase inhibition

Some cancer cells elongate their telomeres through the ALT (alternative lengthening of telomeres) pathway, which is based on homologous recombination for the addition of telomere repeats without telomerase activity. General control non-derepressible 5 (GCN5) and P300/CBP-associated factor (PCAF), tw...

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Detalles Bibliográficos
Autores principales: Bakhos-Douaihy, Dalal, Desmaze, Chantal, Jeitany, Maya, Gauthier, Laurent R., Biard, Denis, Junier, Marie-Pierre, Chneiweiss, Hervé, Boussin, François D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366824/
https://www.ncbi.nlm.nih.gov/pubmed/30774779
http://dx.doi.org/10.18632/oncotarget.26616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366824/
https://www.ncbi.nlm.nih.gov/pubmed/30774779
http://dx.doi.org/10.18632/oncotarget.26616

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