Adipose-derived autotaxin regulates inflammation and steatosis associated with diet-induced obesity

Autotaxin (ATX) is a secreted enzyme that generates the bioactive lipid lysophosphatidic acid (LPA). We generated mice with global inducible post-natal inactivation or adipose-specific loss of the Enpp2 gene encoding ATX. The animals are phenotypically unremarkable and exhibit differences in adipocy...

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Detalles Bibliográficos
Autores principales: Brandon, J. Anthony, Kraemer, Maria, Vandra, Julia, Halder, Suchismita, Ubele, Margo, Morris, Andrew J., Smyth, Susan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366870/
https://www.ncbi.nlm.nih.gov/pubmed/30730895
http://dx.doi.org/10.1371/journal.pone.0208099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366870/
https://www.ncbi.nlm.nih.gov/pubmed/30730895
http://dx.doi.org/10.1371/journal.pone.0208099

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