Clinicopathological characterization of SMAD4-mutated intestinal adenocarcinomas: A case-control study

The SMAD4 tumor suppressor gene product inhibits transforming growth factor-β-mediated signaling and is mutated in ~10% of colorectal carcinomas. The prognostic significance of SMAD4 mutations has been controversial. We studied the pathological and clinical characteristics of SMAD4-mutated intestina...

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Detalles Bibliográficos
Autores principales: Liao, Xiaoyan, Hao, Yansheng, Zhang, Xiaofei, Ward, Stephen, Houldsworth, Jane, Polydorides, Alexandros D., Harpaz, Noam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366887/
https://www.ncbi.nlm.nih.gov/pubmed/30730996
http://dx.doi.org/10.1371/journal.pone.0212142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366887/
https://www.ncbi.nlm.nih.gov/pubmed/30730996
http://dx.doi.org/10.1371/journal.pone.0212142

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