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Clinicopathological characterization of SMAD4-mutated intestinal adenocarcinomas: A case-control study

The SMAD4 tumor suppressor gene product inhibits transforming growth factor-β-mediated signaling and is mutated in ~10% of colorectal carcinomas. The prognostic significance of SMAD4 mutations has been controversial. We studied the pathological and clinical characteristics of SMAD4-mutated intestina...

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Detalles Bibliográficos
Autores principales:	Liao, Xiaoyan, Hao, Yansheng, Zhang, Xiaofei, Ward, Stephen, Houldsworth, Jane, Polydorides, Alexandros D., Harpaz, Noam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366887/ https://www.ncbi.nlm.nih.gov/pubmed/30730996 http://dx.doi.org/10.1371/journal.pone.0212142

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