Pat1 promotes processing body assembly by enhancing the phase separation of the DEAD-box ATPase Dhh1 and RNA

Processing bodies (PBs) are cytoplasmic mRNP granules that assemble via liquid–liquid phase separation and are implicated in the decay or storage of mRNAs. How PB assembly is regulated in cells remains unclear. Previously, we identified the ATPase activity of the DEAD-box protein Dhh1 as a key regul...

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Detalles Bibliográficos
Autores principales: Sachdev, Ruchika, Hondele, Maria, Linsenmeier, Miriam, Vallotton, Pascal, Mugler, Christopher F, Arosio, Paolo, Weis, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366900/
https://www.ncbi.nlm.nih.gov/pubmed/30648970
http://dx.doi.org/10.7554/eLife.41415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366900/
https://www.ncbi.nlm.nih.gov/pubmed/30648970
http://dx.doi.org/10.7554/eLife.41415

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