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Pat1 promotes processing body assembly by enhancing the phase separation of the DEAD-box ATPase Dhh1 and RNA
Processing bodies (PBs) are cytoplasmic mRNP granules that assemble via liquid–liquid phase separation and are implicated in the decay or storage of mRNAs. How PB assembly is regulated in cells remains unclear. Previously, we identified the ATPase activity of the DEAD-box protein Dhh1 as a key regul...
Autores principales: | Sachdev, Ruchika, Hondele, Maria, Linsenmeier, Miriam, Vallotton, Pascal, Mugler, Christopher F, Arosio, Paolo, Weis, Karsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366900/ https://www.ncbi.nlm.nih.gov/pubmed/30648970 http://dx.doi.org/10.7554/eLife.41415 |
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