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Single cell functional genomics reveals the importance of mitochondria in cell-to-cell phenotypic variation

Mutations frequently have outcomes that differ across individuals, even when these individuals are genetically identical and share a common environment. Moreover, individual microbial and mammalian cells can vary substantially in their proliferation rates, stress tolerance, and drug resistance, with...

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Detalles Bibliográficos
Autores principales: Dhar, Riddhiman, Missarova, Alsu M, Lehner, Ben, Carey, Lucas B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366901/
https://www.ncbi.nlm.nih.gov/pubmed/30638445
http://dx.doi.org/10.7554/eLife.38904