Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro

Abnormalities in tricarboxylic acid (TCA) cycle function were related to a variety of pathological processes. Fumarate hydratase (FH) is a required enzyme in the TCA cycle. To explore the general influence of FH knockout, we isolated FH(+/–) rat and normal rat lung fibroblasts and cultured these cel...

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Detalles Bibliográficos
Autores principales: Fan, Zhirui, Li, Lifeng, Li, Xiaoli, Zhang, Meng, Dou, Mengmeng, Zhao, Jing, Cao, Jing, Deng, Xiaoming, Zhang, Mingzhi, Li, Huixiang, Suo, Zhenhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366963/
https://www.ncbi.nlm.nih.gov/pubmed/30668541
http://dx.doi.org/10.18632/aging.101761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366963/
https://www.ncbi.nlm.nih.gov/pubmed/30668541
http://dx.doi.org/10.18632/aging.101761

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