Loss of GPR109A/HCAR2 induces aging-associated hepatic steatosis

GPR109A agonists have been used for the treatment of obesity however, the role of GPR109A in regulating aging-associated alterations in lipid metabolism is unknown. In this study we used Gpr109a(-/-) mice to investigate the effect of aging in the regulation of lipid accumulation. We observed that in...

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Detalles Bibliográficos
Autores principales: Jadeja, Ravirajsinh N., Jones, Malita A., Fromal, Ollya, Powell, Folami L., Khurana, Sandeep, Singh, Nagendra, Martin, Pamela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366969/
https://www.ncbi.nlm.nih.gov/pubmed/30659164
http://dx.doi.org/10.18632/aging.101743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366969/
https://www.ncbi.nlm.nih.gov/pubmed/30659164
http://dx.doi.org/10.18632/aging.101743

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