Chronic hyperglycemia regulates microglia polarization through ERK5

Diabetic patients are prone to developing Alzheimer’s disease (AD), in which microglia play a critical role. However, the direct effect of high glucose (HG) on microglia and the role of extracellular-signal-regulated kinase 5 (ERK5) signaling in this interaction have not been examined before. Here,...

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Detalles Bibliográficos
Autores principales: Chen, Congde, Wu, Suichun, Hong, Zipu, Chen, Xiaoming, Shan, Xiaoou, Fischbach, Shane, Xiao, Xiangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366978/
https://www.ncbi.nlm.nih.gov/pubmed/30684443
http://dx.doi.org/10.18632/aging.101770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366978/
https://www.ncbi.nlm.nih.gov/pubmed/30684443
http://dx.doi.org/10.18632/aging.101770

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