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Modulation of miR-10a-mediated TGF-β1/Smads signaling affects atrial fibrillation-induced cardiac fibrosis and cardiac fibroblast proliferation

Atrial fibrillation (AF) rat models and rat cardiac fibroblasts (CFs) with overexpressed or inhibited miR-10a were used to investigate the possible role of miR-10a-mediated transforming growth factor-β (TGF-β1)/Smads signaling in cardiac fibrosis and fibroblast proliferation in rats with AF. Gene on...

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Detalles Bibliográficos
Autores principales: Li, Peng-Fei, He, Rong-Hua, Shi, Shao-Bo, Li, Rui, Wang, Qiong-Tao, Rao, Guo-Tao, Yang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367129/
https://www.ncbi.nlm.nih.gov/pubmed/30683806
http://dx.doi.org/10.1042/BSR20181931