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Determination of Tobramycin and Vancomycin Exposure Required to Eradicate Biofilms on Muscle and Bone Tissue In Vitro

Background: Bacterial biofilms cause chronic orthopaedic infections. Surgical debridement to remove biofilm can be ineffective without adjuvant local antimicrobials because undetected biofilm fragments may remain in the wound and reestablish the infection if untreated. However, the concentrations an...

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Detalles Bibliográficos
Autores principales: Badha, Vajra, Moore, Rex, Heffernan, John, Castaneda, Paulo, McLaren, Alex, Overstreet, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367195/
https://www.ncbi.nlm.nih.gov/pubmed/30755841
http://dx.doi.org/10.7150/jbji.29711