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A feed-forward loop between nuclear translocation of CXCR4 and HIF-1α promotes renal cell carcinoma metastasis

CXC chemokine receptor 4 (CXCR4) has been suggested to play a critical role in cancer metastasis. Some studies have described CXCR4 nuclear localization in metastatic lesions of renal cell carcinoma (RCC), which has been suggested to be correlated with cancer metastasis. However, the underlying mech...

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Detalles Bibliográficos
Autores principales: Bao, Yi, Wang, Zhixiang, Liu, Bing, Lu, Xin, Xiong, Ying, Shi, Jiazi, Li, Peng, Chen, Junming, Zhang, Zongqin, Chen, Ming, Wang, Linhui, Wu, Zhenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367212/
https://www.ncbi.nlm.nih.gov/pubmed/30177838
http://dx.doi.org/10.1038/s41388-018-0452-4