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Differentially expressed gene networks, biomarkers, long noncoding RNAs, and shared responses with cocaine identified in the midbrains of human opioid abusers

Opioid abuse is now the most common cause of accidental death in the US. Although opioids and most other drugs of abuse acutely increase signaling mediated by midbrain dopamine (DA)-synthesizing neurons, little is known about long-lasting changes in DA cells that may contribute to continued opioid a...

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Detalles Bibliográficos
Autores principales: Saad, Manal H., Rumschlag, Matthew, Guerra, Michael H., Savonen, Candace L., Jaster, Alaina M., Olson, Philip D., Alazizi, Adnan, Luca, Francesca, Pique-Regi, Roger, Schmidt, Carl J., Bannon, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367337/
https://www.ncbi.nlm.nih.gov/pubmed/30733491
http://dx.doi.org/10.1038/s41598-018-38209-8