Notch signaling facilitates hepatitis B virus covalently closed circular DNA transcription via cAMP response element-binding protein with E3 ubiquitin ligase-modulation

Notch1 is regulated by E3 ubiquitin ligases, with proteasomal degradation of the Notch intracellular domain affecting the transcription of target genes. cAMP response element-binding protein (CREB) mediates the transcription of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA). We asse...

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Detalles Bibliográficos
Autores principales: Wang, Zijing, Kawaguchi, Kazunori, Honda, Masao, Hashimoto, Shinichi, Shirasaki, Takayoshi, Okada, Hikari, Orita, Noriaki, Shimakami, Tetsuro, Yamashita, Taro, Sakai, Yoshio, Mizukoshi, Eishiro, Murakami, Seishi, Kaneko, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367350/
https://www.ncbi.nlm.nih.gov/pubmed/30733490
http://dx.doi.org/10.1038/s41598-018-38139-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367350/
https://www.ncbi.nlm.nih.gov/pubmed/30733490
http://dx.doi.org/10.1038/s41598-018-38139-5

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