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Chronic olanzapine administration causes metabolic syndrome through inflammatory cytokines in rodent models of insulin resistance
Olanzapine is a second-generation anti-psychotic drug used to prevent neuroinflammation in patients with schizophrenia. However, the long-term administration of olanzapine leads to insulin resistance (IR); the mechanisms of this effect remains poorly understood. Using cellular and rodent models of I...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367387/ https://www.ncbi.nlm.nih.gov/pubmed/30733507 http://dx.doi.org/10.1038/s41598-018-36930-y |