Chronic olanzapine administration causes metabolic syndrome through inflammatory cytokines in rodent models of insulin resistance

Olanzapine is a second-generation anti-psychotic drug used to prevent neuroinflammation in patients with schizophrenia. However, the long-term administration of olanzapine leads to insulin resistance (IR); the mechanisms of this effect remains poorly understood. Using cellular and rodent models of I...

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Detalles Bibliográficos
Autores principales: Li, Huqun, Peng, Shiyong, Li, Shihong, Liu, Shouqing, Lv, Yifan, Yang, Ni, Yu, Liangyu, Deng, Ya-Hui, Zhang, Zhongjian, Fang, Maosheng, Huo, Yunxiang, Chen, Ying, Sun, Taohua, Li, Weiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367387/
https://www.ncbi.nlm.nih.gov/pubmed/30733507
http://dx.doi.org/10.1038/s41598-018-36930-y

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