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Liver-specific Gene Delivery Using Engineered Virus-Like Particles of Hepatitis E Virus
Virus-like particles (VLPs) possess great potential for organ-specific transport of therapeutic agents due to their central cavity surrounded by viral capsid proteins and similar tropism to their original viruses. The N-terminal truncated second open reading frame (Nt-ORF2) of the hepatotropic hepat...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367430/ https://www.ncbi.nlm.nih.gov/pubmed/30733562 http://dx.doi.org/10.1038/s41598-019-38533-7 |