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Liver-specific Gene Delivery Using Engineered Virus-Like Particles of Hepatitis E Virus

Virus-like particles (VLPs) possess great potential for organ-specific transport of therapeutic agents due to their central cavity surrounded by viral capsid proteins and similar tropism to their original viruses. The N-terminal truncated second open reading frame (Nt-ORF2) of the hepatotropic hepat...

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Detalles Bibliográficos
Autores principales: Lee, Eun Byul, Kim, Jung-Hee, Hur, Wonhee, Choi, Jung Eun, Kim, Sung Min, Park, Dong Jun, Kang, Byung-Yoon, Lee, Gil Won, Yoon, Seung Kew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367430/
https://www.ncbi.nlm.nih.gov/pubmed/30733562
http://dx.doi.org/10.1038/s41598-019-38533-7