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Fast NMR method to probe solvent accessibility and disordered regions in proteins

Understanding protein structure and dynamics, which govern key cellular processes, is crucial for basic and applied research. Intrinsically disordered protein (IDP) regions display multifunctionality via alternative transient conformations, being key players in disease mechanisms. IDP regions are ab...

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Detalles Bibliográficos
Autores principales: Faustino, André F., Barbosa, Glauce M., Silva, Micael, Castanho, Miguel A. R. B., Da Poian, Andrea T., Cabrita, Eurico J., Santos, Nuno C., Almeida, Fabio C. L., Martins, Ivo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367444/
https://www.ncbi.nlm.nih.gov/pubmed/30733478
http://dx.doi.org/10.1038/s41598-018-37599-z