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Fast NMR method to probe solvent accessibility and disordered regions in proteins
Understanding protein structure and dynamics, which govern key cellular processes, is crucial for basic and applied research. Intrinsically disordered protein (IDP) regions display multifunctionality via alternative transient conformations, being key players in disease mechanisms. IDP regions are ab...
Autores principales: | Faustino, André F., Barbosa, Glauce M., Silva, Micael, Castanho, Miguel A. R. B., Da Poian, Andrea T., Cabrita, Eurico J., Santos, Nuno C., Almeida, Fabio C. L., Martins, Ivo C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367444/ https://www.ncbi.nlm.nih.gov/pubmed/30733478 http://dx.doi.org/10.1038/s41598-018-37599-z |
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