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Transcriptome profiling of zebrafish optic fissure fusion

Incomplete fusion of the optic fissure leads to ocular coloboma, a congenital eye defect that affects up to 7.5 per 10,000 births and accounts for up to 10 percent of childhood blindness. The molecular and cellular mechanisms that facilitate optic fissure fusion remain elusive. We have profiled glob...

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Detalles Bibliográficos
Autores principales: Richardson, R., Owen, N., Toms, M., Young, Rodrigo M., Tracey-White, D., Moosajee, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367446/
https://www.ncbi.nlm.nih.gov/pubmed/30733552
http://dx.doi.org/10.1038/s41598-018-38379-5