Cargando…
Transcriptome profiling of zebrafish optic fissure fusion
Incomplete fusion of the optic fissure leads to ocular coloboma, a congenital eye defect that affects up to 7.5 per 10,000 births and accounts for up to 10 percent of childhood blindness. The molecular and cellular mechanisms that facilitate optic fissure fusion remain elusive. We have profiled glob...
Autores principales: | Richardson, R., Owen, N., Toms, M., Young, Rodrigo M., Tracey-White, D., Moosajee, M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367446/ https://www.ncbi.nlm.nih.gov/pubmed/30733552 http://dx.doi.org/10.1038/s41598-018-38379-5 |
Ejemplares similares
-
Closing the Gap: Mechanisms of Epithelial Fusion During Optic Fissure Closure
por: Chan, Brian Ho Ching, et al.
Publicado: (2021) -
In Vivo Analysis of Optic Fissure Fusion in Zebrafish: Pioneer Cells, Basal Lamina, Hyaloid Vessels, and How Fissure Fusion is Affected by BMP
por: Eckert, Priska, et al.
Publicado: (2020) -
Hyaloid vasculature and mmp2 activity play a role during optic fissure fusion in zebrafish
por: Weaver, Megan L., et al.
Publicado: (2020) -
Changes in Mitochondrial Size and Morphology in the RPE and Photoreceptors of the Developing and Ageing Zebrafish
por: Burgoyne, Thomas, et al.
Publicado: (2022) -
Ubiquitin-mediated proteasome degradation regulates optic fissure fusion
por: Pereira Piedade, Warlen, et al.
Publicado: (2019)