Enabling precision medicine by unravelling disease pathophysiology: quantifying signal transduction pathway activity across cell and tissue types

Signal transduction pathways are important in physiology and pathophysiology. Targeted drugs aim at modifying pathogenic pathway activity, e.g., in cancer. Optimal treatment choice requires assays to measure pathway activity in individual patient tissue or cell samples. We developed a method enablin...

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Detalles Bibliográficos
Autores principales: Stolpe, Anja van de, Holtzer, Laurent, van Ooijen, Henk, de Inda, Marcia Alves, Verhaegh, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367506/
https://www.ncbi.nlm.nih.gov/pubmed/30733525
http://dx.doi.org/10.1038/s41598-018-38179-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367506/
https://www.ncbi.nlm.nih.gov/pubmed/30733525
http://dx.doi.org/10.1038/s41598-018-38179-x

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