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MicroRNA-29a is a key regulon that regulates BRD4 and mitigates liver fibrosis in mice by inhibiting hepatic stellate cell activation

MicroRNA-29a is a key regulon that regulates hepatic stellate cells (HSCs) and mitigates liver fibrosis. However, the mechanism by which it does so remains largely undefined. The inhibition of bromodomain-4 protein (BRD4) represents a novel therapeutic target in hepatic fibrosis. Therefore, the purp...

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Detalles Bibliográficos
Autores principales: Huang, Ying-Hsien, Kuo, Hsing-Chun, Yang, Ya-Ling, Wang, Feng-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367521/
https://www.ncbi.nlm.nih.gov/pubmed/30745801
http://dx.doi.org/10.7150/ijms.29930