A Pilot Study of Aberrant CpG Island Hypermethylation of SPRED1 in Acute Myeloloid Leukemia

Background: Epigenetic silencing of tumor suppressor genes plays important role in acute myeloid leukemia (AML). Recently, SPRED1, a negative regulator of the RAS MAPK pathway, is identified as a tumour suppressor downregulated in AML. However, little is known regarding its underlying dysregulation...

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Detalles Bibliográficos
Autores principales: Sun, Jingwen, Zhang, Jinjing, Wang, Yue, Li, Yan, Zhang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367533/
https://www.ncbi.nlm.nih.gov/pubmed/30745814
http://dx.doi.org/10.7150/ijms.27757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367533/
https://www.ncbi.nlm.nih.gov/pubmed/30745814
http://dx.doi.org/10.7150/ijms.27757

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