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Generation of Pigs Resistant to Highly Pathogenic-Porcine Reproductive and Respiratory Syndrome Virus through Gene Editing of CD163

Porcine reproductive and respiratory syndrome (PRRS) is a highly contagious disease and the most economically important disease of the swine industry worldwide. Highly pathogenic-PRRS virus (HP-PRRSV) is a variant of PRRSV, which caused high morbidity and mortality. Scavenger receptor CD163, which c...

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Detalles Bibliográficos
Autores principales: Chen, Jingyao, Wang, Haitao, Bai, Jianhui, Liu, Wenjie, Liu, Xiaojuan, Yu, Dawei, Feng, Tao, Sun, Zhaolin, Zhang, Linlin, Ma, Linyuan, Hu, Yiqing, Zou, Yunlong, Tan, Tan, Zhong, Jie, Hu, Man, Bai, Xiaofei, Pan, Dengke, Xing, Yiming, Zhao, Yaofeng, Tian, Kegong, Hu, Xiaoxiang, Li, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367541/
https://www.ncbi.nlm.nih.gov/pubmed/30745836
http://dx.doi.org/10.7150/ijbs.25862