Verteporfin blocks Clusterin which is required for survival of gastric cancer stem cell by modulating HSP90 function

Gastric cancer stem cell (GCSC) is implicated in gastric cancer relapse, metastasis and drug resistance. However, the key molecule(s) involved in GCSC survival and the targeting drugs are poorly understood. We discovered increased secreted clusterin (S-Clu) protein expression during the sphere-formi...

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Detalles Bibliográficos
Autores principales: Xiong, Jixian, Wang, Shaoxiang, Chen, Tie, Shu, Xingsheng, Mo, Xianming, Chang, Gang, Chen, Jia-Jie, Li, Chenyang, Luo, Hui, Lee, Jiing-Dwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367548/
https://www.ncbi.nlm.nih.gov/pubmed/30745823
http://dx.doi.org/10.7150/ijbs.29135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367548/
https://www.ncbi.nlm.nih.gov/pubmed/30745823
http://dx.doi.org/10.7150/ijbs.29135

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