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RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types

The molecular characterization of immune subsets is important for designing effective strategies to understand and treat diseases. We characterized 29 immune cell types within the peripheral blood mononuclear cell (PBMC) fraction of healthy donors using RNA-seq (RNA sequencing) and flow cytometry. O...

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Detalles Bibliográficos
Autores principales: Monaco, Gianni, Lee, Bernett, Xu, Weili, Mustafah, Seri, Hwang, You Yi, Carré, Christophe, Burdin, Nicolas, Visan, Lucian, Ceccarelli, Michele, Poidinger, Michael, Zippelius, Alfred, Pedro de Magalhães, João, Larbi, Anis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367568/
https://www.ncbi.nlm.nih.gov/pubmed/30726743
http://dx.doi.org/10.1016/j.celrep.2019.01.041