Combined Androgen receptor blockade overcomes the resistance of breast cancer cells to palbociclib

The dysregulation of cyclin D -Cyclin-dependent kinase 4/6 (CDK4/6)-Rb axis has been implicated in breast cancer progression and the selective CDK4/6 inhibitors have shown effective activity in advanced breast cancer, especially in tumors driven by the estrogen receptor (ER). However, resistance to...

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Detalles Bibliográficos
Autores principales: Ji, Wenfei, Shi, Yaqin, Wang, Xin, He, Weiwei, Tang, Lin, Tian, Shengwang, Jiang, Hua, Shu, Yongqian, Guan, Xiaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367574/
https://www.ncbi.nlm.nih.gov/pubmed/30745839
http://dx.doi.org/10.7150/ijbs.30572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367574/
https://www.ncbi.nlm.nih.gov/pubmed/30745839
http://dx.doi.org/10.7150/ijbs.30572

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