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Combined Androgen receptor blockade overcomes the resistance of breast cancer cells to palbociclib
The dysregulation of cyclin D -Cyclin-dependent kinase 4/6 (CDK4/6)-Rb axis has been implicated in breast cancer progression and the selective CDK4/6 inhibitors have shown effective activity in advanced breast cancer, especially in tumors driven by the estrogen receptor (ER). However, resistance to...
Autores principales: | Ji, Wenfei, Shi, Yaqin, Wang, Xin, He, Weiwei, Tang, Lin, Tian, Shengwang, Jiang, Hua, Shu, Yongqian, Guan, Xiaoxiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367574/ https://www.ncbi.nlm.nih.gov/pubmed/30745839 http://dx.doi.org/10.7150/ijbs.30572 |
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