Sirt6 Suppresses High Glucose-Induced Mitochondrial Dysfunction and Apoptosis in Podocytes through AMPK Activation

Previous studies have shown that mitochondrial dysfunction plays an important role in high- glucose(HG)-induced podocyte injury and thus contributes to the progression of diabetic nephropathy(DN). The histone deacetylase Sirtuin6 (Sirt6) has been revealed to have an essential role in the regulation...

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Detalles Bibliográficos
Autores principales: Fan, Yanqin, Yang, Qian, Yang, Yingjie, Gao, Zhao, Ma, Yiqiong, Zhang, Lu, Liang, Wei, Ding, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367578/
https://www.ncbi.nlm.nih.gov/pubmed/30745856
http://dx.doi.org/10.7150/ijbs.29323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367578/
https://www.ncbi.nlm.nih.gov/pubmed/30745856
http://dx.doi.org/10.7150/ijbs.29323

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