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Attenuation of STAT3 Phosphorylation Promotes Apoptosis and Chemosensitivity in Human Osteosarcoma Induced by Raddeanin A

Osteosarcoma (OS) is the most common primary bone malignancy in adolescents. One major obstacle for current OS treatment is drug-resistance. Raddeanin A (RA), an oleanane-type triterpenoid saponin, exerts anti-tumor effects in several tumor models, but the effect of RA in human drug-resistant OS rem...

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Detalles Bibliográficos
Autores principales: Wang, Zhuoying, Wang, Chongren, Zuo, Dongqing, Zhang, Tao, Yin, Fei, Zhou, Zifei, Wang, Hongsheng, Xu, Jing, Mao, Min, Wang, Gangyang, Hua, Yingqi, Sun, Wei, Cai, Zhengdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367581/
https://www.ncbi.nlm.nih.gov/pubmed/30745853
http://dx.doi.org/10.7150/ijbs.30168