Andrographolide Enhances TRAIL-Induced Apoptosis via p53-Mediated Death Receptors Up-Regulation and Suppression of the NF-кB Pathway in Bladder Cancer Cells

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an effective chemotherapeutic agent that specifically impairs cancer cells while sparing normal cells; however, some cancer cells develop resistance to TRAIL. Here, we identified Andrographolide, a diterpenoid lactone derived from a...

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Yuyou, Bi, Ran, Guo, Haoran, Yang, Jiaxin, Du, Yujun, Wang, Chunxi, Wei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367587/
https://www.ncbi.nlm.nih.gov/pubmed/30745855
http://dx.doi.org/10.7150/ijbs.30847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367587/
https://www.ncbi.nlm.nih.gov/pubmed/30745855
http://dx.doi.org/10.7150/ijbs.30847

Ejemplares similares