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miR-9 Enhances the Chemosensitivity of AML Cells to Daunorubicin by Targeting the EIF5A2/MCL-1 Axis

Daunorubicin (Dnr) is at the forefront of acute myeloid leukemia (AML) therapy, but drug resistance poses a major threat to treatment success. MicroRNA (miR)-9 has been shown to have a pivotal role in AML development. However, little is known about the role of miR-9 in Dnr resistance in AML. We expl...

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Detalles Bibliográficos
Autores principales: Liu, Yanhui, Lei, Pingchong, Qiao, Hong, Sun, Kai, Lu, Xiling, Bao, Fengchang, Yu, Runhong, Lian, Cheng, Li, Yao, Chen, Wei, Xue, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367593/
https://www.ncbi.nlm.nih.gov/pubmed/30745844
http://dx.doi.org/10.7150/ijbs.29775