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Macrophage-Derived Slit3 Controls Cell Migration and Axon Pathfinding in the Peripheral Nerve Bridge

Slit-Robo signaling has been characterized as a repulsive signal for precise axon pathfinding and cell migration during embryonic development. Here, we describe a role for Sox2 in the regulation of Robo1 in Schwann cells and for Slit3-Robo1 signaling in controlling axon guidance within the newly for...

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Detalles Bibliográficos
Autores principales: Dun, Xin-peng, Carr, Lauren, Woodley, Patricia K., Barry, Riordan W., Drake, Louisa K., Mindos, Thomas, Roberts, Sheridan L., Lloyd, Alison C., Parkinson, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367597/
https://www.ncbi.nlm.nih.gov/pubmed/30726731
http://dx.doi.org/10.1016/j.celrep.2018.12.081