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Macrophage-Derived Slit3 Controls Cell Migration and Axon Pathfinding in the Peripheral Nerve Bridge
Slit-Robo signaling has been characterized as a repulsive signal for precise axon pathfinding and cell migration during embryonic development. Here, we describe a role for Sox2 in the regulation of Robo1 in Schwann cells and for Slit3-Robo1 signaling in controlling axon guidance within the newly for...
Autores principales: | Dun, Xin-peng, Carr, Lauren, Woodley, Patricia K., Barry, Riordan W., Drake, Louisa K., Mindos, Thomas, Roberts, Sheridan L., Lloyd, Alison C., Parkinson, David B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367597/ https://www.ncbi.nlm.nih.gov/pubmed/30726731 http://dx.doi.org/10.1016/j.celrep.2018.12.081 |
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