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Host mRNA decay proteins influence HIV-1 replication and viral gene expression in primary monocyte-derived macrophages
BACKGROUND: Mammalian cells harbour RNA quality control and degradative machineries such as nonsense-mediated mRNA decay that target cellular mRNAs for clearance from the cell to avoid aberrant gene expression. The role of the host mRNA decay pathways in macrophages in the context of human immunodef...
Autores principales: | Rao, Shringar, Amorim, Raquel, Niu, Meijuan, Breton, Yann, Tremblay, Michel J., Mouland, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367771/ https://www.ncbi.nlm.nih.gov/pubmed/30732620 http://dx.doi.org/10.1186/s12977-019-0465-2 |
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