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Bevacizumab treatment for radiation brain necrosis: mechanism, efficacy and issues
Vascular damage is followed by vascular endothelial growth factor (VEGF) expression at high levels, which is an important mechanism forradiation brain necrosis development. Bevacizumab alleviates brain edema symptoms caused by radiation brain necrosis through inhibiting VEGF and acting on vascular t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367784/ https://www.ncbi.nlm.nih.gov/pubmed/30732625 http://dx.doi.org/10.1186/s12943-019-0950-1 |