Cathepsin L activated by mutant p53 and Egr-1 promotes ionizing radiation-induced EMT in human NSCLC

BACKGROUND: Ionizing radiation (IR) is one of the major clinical therapies of cancer, although it increases the epithelial-mesenchymal transition (EMT) of non-small cell lung cancer (NSCLC), unexpectedly. The cellular and molecular mechanisms underlying this role are not completely understood. METHO...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Wenjuan, Xiong, Yajie, Ding, Xinyuan, Wang, Long, Zhao, Yifan, Fei, Yao, Zhu, Ying, Shen, Xiao, Tan, Caihong, Liang, Zhongqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367810/
https://www.ncbi.nlm.nih.gov/pubmed/30732622
http://dx.doi.org/10.1186/s13046-019-1054-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367810/
https://www.ncbi.nlm.nih.gov/pubmed/30732622
http://dx.doi.org/10.1186/s13046-019-1054-x

Ejemplares similares