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Cathepsin L activated by mutant p53 and Egr-1 promotes ionizing radiation-induced EMT in human NSCLC

BACKGROUND: Ionizing radiation (IR) is one of the major clinical therapies of cancer, although it increases the epithelial-mesenchymal transition (EMT) of non-small cell lung cancer (NSCLC), unexpectedly. The cellular and molecular mechanisms underlying this role are not completely understood. METHO...

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Detalles Bibliográficos
Autores principales:	Wang, Wenjuan, Xiong, Yajie, Ding, Xinyuan, Wang, Long, Zhao, Yifan, Fei, Yao, Zhu, Ying, Shen, Xiao, Tan, Caihong, Liang, Zhongqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367810/ https://www.ncbi.nlm.nih.gov/pubmed/30732622 http://dx.doi.org/10.1186/s13046-019-1054-x

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