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Synergistic cytoprotection by co-treatment with dexamethasone and rapamycin against proinflammatory cytokine-induced alveolar epithelial cell injury

BACKGROUND: One of the main pathophysiological manifestations during the acute phase of sepsis is massive production of proinflammatory mediators. Clinical trials involving direct suppression of inflammatory mediators to relieve organ dysfunction in sepsis have been extensively performed; however, t...

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Detalles Bibliográficos
Autores principales: Kuwajima, Ken, Chang, Kyungho, Furuta, Ai, Bougaki, Masahiko, Uchida, Kanji, Sawamura, Shigehito, Yamada, Yoshitsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367811/
https://www.ncbi.nlm.nih.gov/pubmed/30774959
http://dx.doi.org/10.1186/s40560-019-0365-5