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Is mean heart dose a relevant surrogate parameter of left ventricle and coronary arteries exposure during breast cancer radiotherapy: a dosimetric evaluation based on individually-determined radiation dose (BACCARAT study)

BACKGROUND: Intra-individual heterogeneity of cardiac exposure is an issue in breast cancer (BC) radiotherapy that was poorly considered in previous cardiotoxicity studies mainly based on mean heart dose (MHD). This dosimetric study analyzes the distribution of individually-determined radiation dose...

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Detalles Bibliográficos
Autores principales: Jacob, Sophie, Camilleri, Jérémy, Derreumaux, Sylvie, Walker, Valentin, Lairez, Olivier, Lapeyre, Mathieu, Bruguière, Eric, Pathak, Atul, Bernier, Marie-Odile, Laurier, Dominique, Ferrieres, Jean, Gallocher, Olivier, Latorzeff, Igor, Pinel, Baptiste, Franck, Denis, Chevelle, Christian, Jimenez, Gaëlle, Broggio, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367844/
https://www.ncbi.nlm.nih.gov/pubmed/30732640
http://dx.doi.org/10.1186/s13014-019-1234-z