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Mechanical regulation of macrophage function - cyclic tensile force inhibits NLRP3 inflammasome-dependent IL-1β secretion in murine macrophages

Mechanical stress maintains tissue homeostasis by regulating many cellular functions including cell proliferation, differentiation, and inflammation and immune responses. In inflammatory microenvironments, macrophages in mechanosensitive tissues receive mechanical signals that regulate various cellu...

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Detalles Bibliográficos
Autores principales: Maruyama, Kentaro, Nemoto, Eiji, Yamada, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367847/
https://www.ncbi.nlm.nih.gov/pubmed/30774738
http://dx.doi.org/10.1186/s41232-019-0092-2