Cargando…
Mechanical regulation of macrophage function - cyclic tensile force inhibits NLRP3 inflammasome-dependent IL-1β secretion in murine macrophages
Mechanical stress maintains tissue homeostasis by regulating many cellular functions including cell proliferation, differentiation, and inflammation and immune responses. In inflammatory microenvironments, macrophages in mechanosensitive tissues receive mechanical signals that regulate various cellu...
Autores principales: | Maruyama, Kentaro, Nemoto, Eiji, Yamada, Satoru |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367847/ https://www.ncbi.nlm.nih.gov/pubmed/30774738 http://dx.doi.org/10.1186/s41232-019-0092-2 |
Ejemplares similares
-
Cyclic Stretch Negatively Regulates IL-1β Secretion Through the Inhibition of NLRP3 Inflammasome Activation by Attenuating the AMP Kinase Pathway
por: Maruyama, Kentaro, et al.
Publicado: (2018) -
Cyclic Stretch Force Induces Periodontal Ligament Cells to Secrete Exosomes That Suppress IL-1β Production Through the Inhibition of the NF-κB Signaling Pathway in Macrophages
por: Wang, Zhuyu, et al.
Publicado: (2019) -
Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation
por: Ives, Annette, et al.
Publicado: (2015) -
Volcanic Ash Activates the NLRP3 Inflammasome in Murine and Human Macrophages
por: Damby, David E., et al.
Publicado: (2018) -
Internalization of the Membrane Attack Complex Triggers NLRP3 Inflammasome Activation and IL-1β Secretion in Human Macrophages
por: Diaz-del-Olmo, Ines, et al.
Publicado: (2021)