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Sensitively distinguishing intracellular precursor and mature microRNA abundance

Mature microRNAs (miRNAs) produced from precursor microRNAs (pre-miRNAs) by the RNase Dicer have showed significant potential for cancer diagnosis and prognosis due to their key regulatory roles in various pathological processes. However, discriminatory detection of low-abundance miRNAs and pre-miRN...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Cheng, Yaru, Cao, Yu, Dong, Haifeng, Lu, Huiting, Zhang, Kai, Meng, Xiangdan, Liu, Conghui, Zhang, Xueji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368210/
https://www.ncbi.nlm.nih.gov/pubmed/30842835
http://dx.doi.org/10.1039/c8sc03305f