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Transforming growth factor β-induced epithelial-to-mesenchymal signature predicts metastasis-free survival in non-small cell lung cancer

Transforming growth factor beta (TGFβ) plays a key role in regulating epithelial-to-mesenchymal transition (EMT). A gene expression signature (TGFβ-EMT) associated with TGFβ-induced EMT activities was developed using human Non-Small Cell Lung Carcinoma (NSCLC) cells treated with TGFβ-1 and subjected...

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Detalles Bibliográficos
Autores principales: Gordian, Edna, Welsh, Eric A., Gimbrone, Nicholas, Siegel, Erin M., Shibata, David, Creelan, Ben C., Cress, William Douglas, Eschrich, Steven A., Haura, Eric B., Muñoz-Antonia, Teresita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368226/
https://www.ncbi.nlm.nih.gov/pubmed/30783512
http://dx.doi.org/10.18632/oncotarget.26574