Targeted human cytolytic fusion proteins at the cutting edge: harnessing the apoptosis-inducing properties of human enzymes for the selective elimination of tumor cells

Patient-specific targeted therapy represents the holy grail of anti-cancer therapeutics, allowing potent tumor depletion without detrimental off-target toxicities. Disease-specific monoclonal antibodies have been employed to bind to oncogenic cell-surface receptors, representing the earliest form of...

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Detalles Bibliográficos
Autores principales: Mungra, Neelakshi, Jordaan, Sandra, Hlongwane, Precious, Naran, Krupa, Chetty, Shivan, Barth, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368230/
https://www.ncbi.nlm.nih.gov/pubmed/30783518
http://dx.doi.org/10.18632/oncotarget.26618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368230/
https://www.ncbi.nlm.nih.gov/pubmed/30783518
http://dx.doi.org/10.18632/oncotarget.26618

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