Inhibition of ATM kinase upregulates levels of cell death induced by cannabidiol and γ-irradiation in human glioblastoma cells

Despite advances in glioblastoma (GBM) therapy, prognosis of the disease remains poor with a low survival rate. Cannabidiol (CBD) can induce cell death and enhance radiosensitivity of GBM but not normal astrocytes. Inhibition of ATM kinase is an alternative mechanism for radiosensitization of cancer...

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Detalles Bibliográficos
Autores principales: Ivanov, Vladimir N., Wu, Jinhua, Wang, Tony J.C., Hei, Tom K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368233/
https://www.ncbi.nlm.nih.gov/pubmed/30783513
http://dx.doi.org/10.18632/oncotarget.26582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368233/
https://www.ncbi.nlm.nih.gov/pubmed/30783513
http://dx.doi.org/10.18632/oncotarget.26582

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