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Enhanced phosphatidylserine-selective cancer therapy with irradiation and SapC-DOPS nanovesicles

Normal living cells exhibit phosphatidylserine (PS) primarily within the intracellular leaflet of the plasma membrane. In contrast, viable cancer cells have high levels of PS on the external surface, and exhibit a broad range of surface PS, even within specific types of cancer. Agents that target su...

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Detalles Bibliográficos
Autores principales: Davis, Harold W., Vallabhapurapu, Subrahmanya D., Chu, Zhengtao, Vallabhapurapu, Swarajya L., Franco, Robert S., Mierzwa, Michelle, Kassing, William, Barrett, William L., Qi, Xiaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368238/
https://www.ncbi.nlm.nih.gov/pubmed/30783515
http://dx.doi.org/10.18632/oncotarget.26615