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In situ imaging of aminopeptidase N activity in hepatocellular carcinoma: a migration model for tumour using an activatable two-photon NIR fluorescent probe

CD13/aminopeptidase N (APN), which is a zinc-dependent metalloproteinase, plays a vital role in the growth, migration, angiogenesis, and metastasis of tumours. Thus, in situ molecular imaging of endogenous APN levels is considerably significant for investigating APN and its different functions. In t...

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Detalles Bibliográficos
Autores principales: Li, Haidong, Li, Yueqing, Yao, Qichao, Fan, Jiangli, Sun, Wen, Long, Saran, Shao, Kun, Du, Jianjun, Wang, Jingyun, Peng, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368242/
https://www.ncbi.nlm.nih.gov/pubmed/30842824
http://dx.doi.org/10.1039/c8sc04685a